Pengaruh Pemberian Jus Buah Pepaya (Carica papaya L.) terhadap Penurunan Kadar Malondialdehid dan Asam Urat
DOI:
https://doi.org/10.30872/mpc.v12i.131Keywords:
Malondialdehid, papaya fruit, free radicalsAbstract
Malondialdehyde (MDA) is a biomarker of oxidative stress due to the presence of free radicals in the body. Papaya fruit contains vitamin C and ?-carotene which are useful as antioxidants. This study aims to determine the initial description of MDA levels in urine and uric acid in smoker and non-smoker respondents and to determine changes in urinary MDA and uric acid levels after administration of papaya fruit juice (Carica papaya L). The research method used was experimental with a pre-post test design. The results obtained at the initial MDA level of urine of smokers and non-smokers were an average of 2.504 nmol / mL and 1.821 nmol / mL and the results obtained after giving the juice on day 7 were 1.455 nmol / mL and 0.992 nmol / mL . Meanwhile, the initial uric acid levels of each respondent were 9.6 mg / dL and 8.4 mg / dL and the results obtained after giving the juice on day 7 were 7.8 mg / dL and 6.8 mg / dL. . So it can be concluded that the provision of papaya fruit juice can reduce the levels of MDA in urine and uric acid.
References
Dulce, M., Pastrana, R., Gardea, A., Elhadi, M., Miguel, A., dkk. 2014. Effect of UV-C irradiation and low temperature storage on bioactive compounds, antioxidant enzymes and radical scavenging activity of papaya fruit. Journal of Food Science and Technology. 51 (12): 3821-3829
Ermis B, Ors R, Yildirim A, Tasytekin A, Kardas F, Akcay F. 2004. Influence of Smoking on Maternal and Neonatal Serum Malondialdehyde, Superoxide Dismutase and Glutathione Peroxidase Levels. Annuals of Clin. Of Lab. Science. 34 (4): 405- 409.
Fitria, Triandhini RINK R., Mangimbulude JC, Karwur FF. 2013. Merokok dan oksidasi DNA. Sains Medika 5(2):13-120.
Irawan, R, 2013, Hubungan Obesitas terhadap Kadar Malondialdehid(MDA)Plasma pada Mahasiswa Program Studi Pendidikan Dokter UIN Syarif Hidayatullah Jakarta 2013, Laporan Penelitian, Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Islam Negeri Syarif Hidayatullah, Jakarta.
Kamalah, R. dan Umi K. 2019. Pengaruh Ekstrak Teh Hijau Terhdap Kadar FSH, MDA Ovarium Dan Diameter Folikel Pada Tikus Yang Dipapar MSG. Qanun Medika Vol.3 No.1.
Kikuzaki, H., Hisamoto, M., Hirose, K., Akiyama, K., and Taniguci, H., 2002, Antioxidant Properties of Ferulic Acid and Its Related Compounds, J.Agric. Food Chem, 50, 2161-2168.
Komnas Lansia Penyakit Degeneratif. 2010. Warta Kesra edisi 121/15-30.
Lingga, Lanny. 2012. Bebas Penyakit Asam Urat Tanpa Obat. AgroMediaPustaka: Jakarta.
Makaryani I, Amalia L, Ramadhani NR, Pertiwi KI, Aprillia DW. 2014. Pengaruh pemberian pangan antioksidan terhadap kadar malondialdehid plasma mahasiswi pengonsumsi gorengan. JGKI 10(3):21-28.
Oberley, T. D., Zheng,W., Szweda, L.I., and Oberley, L. W., 2000, Localization of Antioxidants Enzymes and Oxidative Damage Products in Normal and Malignant Prostate Epithelium, The Prostate, 44 : 144-155.
Patil, SB, Kodliwadmath, MV & Sheela, MK,2008, Correlation Between Lipid Peroxidation and Non-enzymatic Antioxidant in Pregnancy Induced Hypertension?, Indian Journal of Clinical Biochemistry, vol. 23, no. 1, hal. 45-4.
Prakash, Aruna, Fred Rigelhof, dan Eugene Miller. 2001. Antioxidant Activity Medallion Laboratories: Analithycal Progress. A publication of Medallion Labs : 1-4.
Surtiningsih. 2005. Cantik dengan Bahan Alami. Jakarta: PT. Elex Media Komputido.
Sustrani L. 2008. Asam Urat. PT Gramedia Pustaka Utama. Jakarta.
Turner JE, Hodges NJ, Bosch JA, Aldred S. 2011. Prolonged Depletion of Antioxidant Capacity after Ultra endurance Exercise. Med. Sei. Sports Exerc 43(9):1770-1776.
Winarsi, H. 2007. Antioksidan Alami dan Radikal Bebas: Potensi dan Aplikasinya dalam Kesehatan. Penerbit Kanisius. Yogyakarta
Zakaria FR, Susanto H, Hartoyo. 2000. Pengaruh konsumsi jahe (Zingiber officinale roscoe) terhadap kadar malondialdehid dan vitamin E plasma pada mahasiswa pesantren Ulil Albaab Kedung Badak, Bogor. JTIP 11:36-40.
Downloads
Published
Issue
Section
License
Copyright (c) 2020 Janette Rindana Paranoan, Harra Ismi Farah, Adam M. Ramadhan (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
